The NFL kicks off in earnest Sunday, Sept. 11 with a full slate of games after the Bills and Rams opened up the season on Thursday Night Football.
Both the 1 p.m. and 4:25 p.m. ET windows feature a full slate, including several divisional matchups. The AFC champion Bengals will begin their conference title defense against the Steelers, who are living in the post-Ben Roethlisberger era. Matt Ryan will begin his new life in Indianapolis against the Texans, whereas the Patriots and Mac Jones look to take the next step against Tua Tagovailoa, Tyreek Hill, and the Dolphins. The Saints and Falcons also open the season against each other in an NFC South showdown that features two teams with no love lost.
In the late window, the Packers will begin life without Davante Adams against the Vikings, while the Raiders and Chargers run back a thrilling grudge match from Week 18 last year that saw Las Vegas win and move on to the postseason. In an inter-conference matchup, Patrick Mahomes takes on newly extended Kyler Murray in Chiefs vs. Cardinals.
Finally, in the prime-time windows, the Buccaneers open their season against the Cowboys for the second year in a row, while Russell Wilson returns to Seattle as a member of the Broncos to begin the next chapter of his career.
MORE: Watch NFL games live with fuboTV (free trial)
It’s an all-gas-no-brakes weekend of NFL action. Here’s what to know to follow along and watch.
Here’s the full Week 1 schedule of the NFL season, plus final scores and how to watch every game live.
Note: national broadcasts are listed in bold
| Game | Time (ET) | TV channel |
|---|---|---|
| Buffalo Bills vs. Los Angeles Rams | 8:20 p.m. | NBC, fuboTV |
| Game | Time (ET) | TV channel |
|---|---|---|
| Philadelphia Eagles vs. Detroit Lions | 1 p.m. | FOX, fuboTV |
| San Francisco 49ers vs. Chicago Bears | 1 p.m. | FOX, fuboTV |
| New England Patriots vs. Miami Dolphins | 1 p.m. | CBS, fuboTV |
| Pittsburgh Steelers vs. Cincinnati Bengals | 1 p.m. | CBS, fuboTV |
| Cleveland Browns vs. Carolina Panthers | 1 p.m. | CBS, fuboTV |
| Indianapolis Colts vs. Houston Texans | 1 p.m. | CBS, fuboTV |
| New Orleans Saints vs. Atlanta Falcons | 1 p.m. | FOX, fuboTV |
| Baltimore Ravens vs. New York Jets | 1 p.m. | CBS, fuboTV |
| Jacksonville Jaguars vs. Washington Commanders | 1 p.m. | FOX, fuboTV |
| Green Bay Packers vs. Minnesota Vikings | 4:25 p.m. | FOX, fuboTV |
| New York Giants vs. Tennessee Titans | 4:25 p.m. | FOX, fuboTV |
| Las Vegas Raiders vs. Los Angeles Chargers | 4:25 p.m. | CBS, fuboTV |
| Kansas City Chiefs vs. Arizona Cardinals | 4:25 p.m. | CBS, fuboTV |
| Tampa Bay Buccaneers vs. Dallas Cowboys | 8:20 p.m. | NBC, fuboTV |
| Game | Time (ET) | TV channel |
|---|---|---|
| Denver Broncos vs. Seattle Seahawks | 8:15 p.m. | ESPN, fuboTV |
The NFL season is back with a trio of prime-time games, starting with the Bills-Rams clash on Thursday. The Buccaneers and Cowboys will open their seasons against each other for the second straight year on Sunday night followed by the Broncos heading to Seattle for an instant grudge match between Russell Wilson and his old stomping grounds. There will be a separate Monday Night Football ManningCast, carried on ESPN2 and ESPN+, that will feature both Peyton and Eli Manning.
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The slates are full at 1 p.m. and 4:25 p.m. ET on Sunday with a number of exciting matchups, including Steelers vs. Bengals at 1 p.m. and Chiefs vs. Cardinals at 4:25 p.m. Check your local listings to see which games will be on your broadcast.
Viewers in Canada can watch NFL games on DAZN.
| Game | Score |
|---|---|
| Buffalo Bills vs. Los Angeles Rams | 31-10 |
| Game | Score |
|---|---|
| Philadelphia Eagles vs. Detroit Lions | – |
| San Francisco 49ers vs. Chicago Bears | – |
| New England Patriots vs. Miami Dolphins | – |
| Pittsburgh Steelers vs. Cincinnati Bengals | – |
| Cleveland Browns vs. Carolina Panthers | – |
| Indianapolis Colts vs. Houston Texans | – |
| New Orleans Saints vs. Atlanta Falcons | – |
| Baltimore Ravens vs. New York Jets | – |
| Jacksonville Jaguars vs. Washington Commanders | – |
| Green Bay Packers vs. Minnesota Vikings | – |
| New York Giants vs. Tennessee Titans | – |
| Las Vegas Raiders vs. Los Angeles Chargers | – |
| Kansas City Chiefs vs. Arizona Cardinals | – |
| Tampa Bay Buccaneers vs. Dallas Cowboys | – |
| Game | Score |
|---|---|
| Denver Broncos vs. Seattle Seahawks | – |
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